Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSHSPIATVAQALRRAERILVITGAGLSADSGMPTYRGLGGLYNGRTEEGLPIEAALSGPMLRRDPALCWKYLAELGKACLAARPNAGHEAIAELQKHKPECWVLTQNIDGFHRQAGSPAERLIEIHGELAPLYCQSCGAE---SGGLEEHLHGQLPPRCAACGG-VLRPPVVLFEEMLPEEAIDTLYRELR--KGFDAVLVVGTT------ASFPYIVEPVLRTRQAGGFTAEVNPGVTDLSERVDVKMTGRALDIMPQVVSHIYR 4TWJ Chain:A ((5-248)) ------IRKAAEILAKSKHAVVFTGAGISAE-----------------PEEV---ASISG--FKRNPRAFWEFSMEM-KDKLFAEPNPAHYAIAELERMGIVKAVITQNIDMLHQRAGS--RRVLELHGSMDKLDCLDCHETYDWSEFVEDFNKGEI-PRCRKCGSYYVKPRVVLFGEPLPQR---TLFEAIEEAKHCDAFMVVGSSLVVYPAAELPYI------AKKAGAKMIIVNAEPTMADPIFDVKIIGKAGEVLPKIVEEVKR

General information: TITO was launched using: RESULT: Template: 4TWJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -119197 for 1743 contacts (-68.4/contact) + 2D Compatibility (PS) -23600 + (NN) -14062 + (LL) 744 1D Compatibility (HY) -17200 + (ID) 4350 Total energy: -177665.0 ( -101.93 by residue) QMean score : 0.526

(partial model without unconserved sides chains): PDB file : Tito_4TWJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TWJ-query.scw PDB file : Tito_Scwrl_4TWJ.pdb: