Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDT---------HLSIDFMDVSSYHGGTESTGEVQIIK-DLGSSIENKDVLIIEDILETGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGTLKPEVYSN 4RAN Chain:A ((30-204)) ---DLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLK-------------VIGGD--STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHV----------

General information: TITO was launched using: RESULT: Template: 4RAN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -112769 for 1148 contacts (-98.2/contact) + 2D Compatibility (PS) -16183 + (NN) -1250 + (LL) 624 1D Compatibility (HY) -18800 + (ID) 2550 Total energy: -150928.0 ( -131.47 by residue) QMean score : 0.585

(partial model without unconserved sides chains): PDB file : Tito_4RAN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RAN-query.scw PDB file : Tito_Scwrl_4RAN.pdb: