Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTMKQFEIAAIPGDGVGKEVVAAAEKVLHTAAEVHGGLSFSFTAFPWSCDYYLEHGKMMPEDGIHTLTQFEAVFLGAVGNPK-LVPDHISLWGLLLKIRRELELSINMRPAKQMAGIT--SPLLH---PNDFDFVVIRENSEGEYSEVGGRIHRGDDEIAIQNAVFTRKATERVMRFAFELAKKRRSHVTSATKSNGIYHAMPFWDEVFQQTAADYSGIETSSQHIDALAAFFVTRPETFDVIVASNLFGDILTDISSSLMGSIGIAPSANINPSGKYPSMFEPVHGSAPDIAGQGLANPIGQIWTAKLMLDH-FGEEELGAKILDVMEQVTADGIKTRDIGGQS--TTAEVTDEICSRLRKL 3UDU Chain:C ((6-357)) ----TYKVAVLAGDGIGPLVMKEALKILTFIAQKYN-FSFELNEAKIGGASIDAYGVALSDETLKLCEQSDAILFGSVGGPKW--IDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLKNEIIQKGVDILCVRELTGGIYF---GKQDLGK-ESAYDTEIYTKKEIERIARIAFESARIRKKKVHLIDKANVLASSI-LWREVVANVAKDYQDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKG--FGLYEPAGGSAPDIAHLNIANPIAQILSAALMLKYSFKEEQAAQDIENAISLALAQGKMTKDLNAKSYLNTDEMGDCILEILKE-

General information: TITO was launched using: RESULT: Template: 3UDU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1922 -198094 -103.07 -584.35 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain C : 0.76 3D Compatibility (PKB) : -103.07 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_3UDU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UDU-query.scw PDB file : Tito_Scwrl_3UDU.pdb: