Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----MSKKTIAVIGSGAAALSLAAAFPPSYEVTVITKKSVKNSNSVYAQGGIAAAYAKDDSIEAHLEDTLYAGCGHNNLAIVADVLHDGKMMVQSLLERGFPFDRNERGGVCLGREGAHSYNRIFHAGGDATGRLLIDYLLKRIN--SKIKLIENETAADLLIE--------DGRCIGVMTKD-SKGRLKVRHADEVVLAAGGCGNLFLHHTNDLTVTGDGLSLAYRAGAELTDLEFTQFHPTLLVKNGVSYGLVSEAVRGEGGCLVDENGRRIMAERHPLGDLAPRDIVSRVIHEEMAKGN--RVYIDFSAI--SDFETRFPTITAICEKA-GIDIHSGKIPVAPGMHFLMGGVSVNRWGETTVPGLYAIGETACSGLHGANRLASNSLLEALVFGKRAAEHIIQK-------PVYNRQYQSGLETSVFYEVPDIEG------HELQSKMTSHMSILREQSSLIELSIWLHTLPFQEVNVK---DITIRQMELSHLWQTAKLMTFSALLREESRGAHFRTDFPHAE---VSWQGRQIVHTKKGTKIRKNEGIWNNESFTAEKITESLFS 1CHU Chain:A ((2-533)) NTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEFDE-------------TDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVL-----------------------------------TTLVSKALNHPNIRVLERTNAVDLIV-SDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG-LGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAEDITRRMHDISTLPPWDESRVEN-----PDERV----VIQHNWHELRLFMWDYVGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRKESRGLHFTLD--YPELLT--HSGPSILSP-----------------------------

General information: TITO was launched using: RESULT: Template: 1CHU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2444 -18614 -7.62 -42.40 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -7.62 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_1CHU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CHU-query.scw PDB file : Tito_Scwrl_1CHU.pdb: