Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKML-------QDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQ-STKVP--------QTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH 3MWU Chain:A ((29-356)) --------------------------------------------------------------------MLGKGSFGEVLKCKDRITQQEYAVKVINKASAKNKDTSTILREVELLKKLDH-PNIMKLFEILED----SSSFYIVGELYTGGELFDEIIKR--KRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIKIIDFGLSTCFQQN----DRIGTAYYIAPEVLRG-TYDEKCDVWSAGVILYILLSGTPPFYGKNEYDILK----RVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLK

General information: TITO was launched using: RESULT: Template: 3MWU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131930 for 2306 contacts (-57.2/contact) + 2D Compatibility (PS) -32573 + (NN) -12682 + (LL) 1348 1D Compatibility (HY) -23200 + (ID) 5700 Total energy: -204737.0 ( -88.78 by residue) QMean score : 0.378

(partial model without unconserved sides chains): PDB file : Tito_3MWU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MWU-query.scw PDB file : Tito_Scwrl_3MWU.pdb: