Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKML-------QDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQ-STKVP--------QTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH 3IGO Chain:A ((29-356)) --------------------------------------------------------------------MLGKGSFGEVLKCKDRITQQEYAVKVINKASAKNK-TSTILREVELLKKLDH-PNIMKLFEILED----SSSFYIVGELYTGGELFDEIIKR--KRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIKIIDFGLSTCFQQNT-------TAYYIAPEVLRG-TYDEKCDVWSAGVILYILLSGTPPFYGKNEYDILK----RVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLK

General information: TITO was launched using: RESULT: Template: 3IGO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -124430 for 2279 contacts (-54.6/contact) + 2D Compatibility (PS) -32183 + (NN) -11813 + (LL) 1412 1D Compatibility (HY) -23200 + (ID) 5650 Total energy: -195864.0 ( -85.94 by residue) QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_3IGO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IGO-query.scw PDB file : Tito_Scwrl_3IGO.pdb: