Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELHAITDDSKPVEELARIII-TIQNEVDFIHIRERSKSAA---------DILKLLDLIFEGGI-DKRKLVMNGRVDIALFSTIHRVQLPSGSFSPKQIRARF-PHLHIGRSVHSLEEAVQAEKEDADYVLFGHVFETDCKKGLEGRGVSLLSDIKQ-RISIPVIAIGGMTPDRLRDVKQAGADGIAVMSGIFSSAEPLEAARRYSRKLKEMRYEKAL 3O63 Chain:A ((31-242)) -RLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAAGDADYFCVGPCWPTPT-----APGLGLVRVAAEL--DKPWFAIGGINAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA------

General information: TITO was launched using: RESULT: Template: 3O63.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1050 -141358 -134.63 -740.09 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -134.63 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.512

(partial model without unconserved sides chains): PDB file : Tito_3O63.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3O63-query.scw PDB file : Tito_Scwrl_3O63.pdb: