Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVRHFLSFMDYSPEELIGLIRRGSELKDLRNRGVLYEPLKSRVLGMVFEKASTRTRLSFEAGMIQLGGQAIFLSPRDTQLGRGEPIGDSARVMSRMLDGVMIRTFAHATLTEFAAHSKVPVINGLSDDLHPCQLLADMQTFHEHRGSIQGKTVAWIGDGN-NMCNSYIEAALKFDFQLRVACPEGYEPKAEFVALA-------GDRLRVVRDPREAVAGAHLVSTDVWASMGQEDEAAARIALFRPYQVNAALLDGAADDVLFMHCLPAHRGEEISEELLDDPRSVAWDQAENRLHAQKALLELLIEHAHYA 2I6U Chain:A ((2-306)) --IRHFLRDDDLSPAEQAEVLELAAELKKDPVS--RRPLQGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGLDRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKALLVWLLER----

General information: TITO was launched using: RESULT: Template: 2I6U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -165412 for 2699 contacts (-61.3/contact) + 2D Compatibility (PS) -32635 + (NN) -18133 + (LL) 624 1D Compatibility (HY) -23600 + (ID) 6650 Total energy: -245806.0 ( -91.07 by residue) QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_2I6U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I6U-query.scw PDB file : Tito_Scwrl_2I6U.pdb: