Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKMSLFQNMKSKLLPIAAVSVLTAGIFAGAELQQTEKASAKKQDKAEIRNVIVMIGDGMGTPYIRAYRSMKNNGDTPNNPKLTEFDRNLTGMM-MTHPDDPDYNITDSAAAGTALATGVKTYNNAIGVDKNG------------KKVKSVLEEAKQQGKSTGLVATSEINHATPAAYGAHNESRKNM---------------DQIANSYMDDKIKGKHKIDVLLGGGKSYFNRKD---------------RNLTKEFKQ------AGYSYVTTKQALKKN---KDQQVLGLFADGGLAKALDRD-SKTPSLKDMTVSAIDRLNQNKKGFFLMVEGSQIDWAAHDNDTVGAMSEVKDFEQAYKAAIEFAKKDKHTLVIATADHTTGGFTIGANGEKNWHAEPIL-SAKKTPEFMAK-KISE---GKPVKDVLARYANLKVTSEEIKSVEAAAQADKSKGASKAIIKIFNTRSNSGWTSTDHTGEEVPVYAYGPGKEKFRGLINNTDQANIIFKILKTGK 1K7H Chain:A ((22-469)) ------------------------------------------KLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNT--DKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFR--EPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIANTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTD-PEETIILVTADHGHTLTITGYADR---NT-DILDFAGISDLDDRRYTILDYGSGPGYHI-TEDGKRYEPTEEDLKDI------------------NFRYASAAPKHSATHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVG-

General information: TITO was launched using: RESULT: Template: 1K7H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2557 -110339 -43.15 -282.92 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -43.15 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.440

(partial model without unconserved sides chains): PDB file : Tito_1K7H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1K7H-query.scw PDB file : Tito_Scwrl_1K7H.pdb: