Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKGIIRFLLVSFVLFFALSTGITGVQAAPASSKTSADLEKAEVFGDIDMTTSKKTTVIVELKEKSLAEAKEAGESQSKSKLKTARTKAKNKAIKAVKNGKVNREYEQVFSGFSMKLPANEIPKLLAVKDVKAVYPNVTYKTDNMKDKDVTISEDAVSPQMDDSAPYIGANDAWDLGYTGKGIKVAIIDTGVEYNHPDLKKNFGQYKGYDFVDNDYDPKETPTGDPRGEATDHGTHVAGTVAAN------------GTIKGVAPDATLLAYRVLGPGGSGTTENVIAGVERAVQDGADVMNLSLGNSLN--NPDWATSTALDWAMSEGVVAVTSNGNSGPNGWTVGSPGTSREAISVGATQLPLNEYAVTFGSYSSAKVMG---YNKEDDVKALNNKEVELVEAGIGEAKDFEGKDLTGKVAVVKRGSIAFVDKADNAKKAGAIGMVVYNNLSGEIEANVPGMSVPTIKLSLEDGEKLVSALKAGETKTTFKLTVSKALGE----QVADFSSRGP-VMDTWMIKPDISAPGVNIVSTIPT--------HDPDHPYGYGSKQGTSMASPHIAGAVAVIKQAKPKWSVEQIKAAIMNTAVTLKDSDGEVYPHN--------AQGAGSARIMNAIKADSLVSPGSYSYGTFLKENGNETKNETFTIENQSSIRKSYTLEYSFNGSGISTSGTSRVVIPAHQTGKATAKVKVNTKKTKAGTYEGTVIVREGGKTVAKVPTLLIVKEPDYPRVTSVSVSEGSVQGTYQIETYLPAGAEELAFLVYDSNLDFAGQAGIYKNQDKGYQYFDWDGTINGGTKLPAGEYYLLAYAANKGKSSQVLTEEPFTVE 3I6S Chain:A ((1-649)) ----------------------------------TTHTSDFLKL--------------------------------NPSSGLWPASGLGQDVIVAVLDSG---------------------------------IWPE---------------SASFQDDGMPEIPKRWKGICKPGTQFNASMCNRKLI--GANYFNKGILAN----------DPTVNITMNSARDTDG----HGTHCASITAGNFAKGVSHFGYAPGTARGVAPRARLAVYKFSFNEGT-FTSDLIAAMDQAVADGVDMISISYGYRFIPLYEDAISIASFG-AMMKGVLVSASAGNRGPGIGSLNNGSPW--ILCVASGHTD-RTFAGTLTLGNGLKIRGWSLFPARAFVRDSPVIYNKTLSDCSSEELLSQVENPENTIVICDDNG-DFSDQMRIITRARLKAAIFISE--DPGVFRSATFPNPGVVVNKKEGKQVINYVKNSVTPTATITFQETYLDTKPAPVVAASSARGPSRSYLGISKPDILAPGVLILAAYPPNVFATSIGTNILLSTDYILESGTSMAAPHAAGIAAMLKAAHPEWSPSAIRSAMMTTADPLDNTRKPIKDSDNNKAATPLDMGAGHVDPNRALDPGLVYDATPQDYVNLLCSLN-------FTEEQFKTIARSSASHCSNPSADLNYPSFIALYSIEGNFTLLEQKFKRTVTNVGAATYKAKLKAPKNSTISVSPQILVFKNNE---------------KQSYTLTIRYIGDSRNVGSITWVEQ-----------------------------------------NGNHSVRSPIVTSPIIEVW-

General information: TITO was launched using: RESULT: Template: 3I6S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3939 120087 30.49 198.82 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 30.49 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.293

(partial model without unconserved sides chains): PDB file : Tito_3I6S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3I6S-query.scw PDB file : Tito_Scwrl_3I6S.pdb: