Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIMLTPMQTEEFRSYLTYTTKHYAEEKVKAGTWLPEDAQLLSKQVFTDLLPRGLETPHHHLWSLKLNEKDIVGWLWIHAEPEHPQQEAFIYDFGLYEPYRGKGYAKQALAALDQAARSMG-IRKLSLHVFAHNQTARKLYEQTGFQETDVVMSKKL 2I79 Chain:A ((3-150)) YELLIREAEPKDAAELVAFLNRVSLETDFT--SLDGDG-ILLTSEEMEIFLNKQASSDNQITLLAFLN-GKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNGLGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQ-----

General information: TITO was launched using: RESULT: Template: 2I79.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 614 -72451 -118.00 -492.86 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -118.00 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.527

(partial model without unconserved sides chains): PDB file : Tito_2I79.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I79-query.scw PDB file : Tito_Scwrl_2I79.pdb: