Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD---DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 2HXQ Chain:A ((8-263)) ------------------------WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKR---CPEN--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVF-------------RYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRP------------------------

General information: TITO was launched using: RESULT: Template: 2HXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -133664 for 1935 contacts (-69.1/contact) + 2D Compatibility (PS) -25827 + (NN) -2651 + (LL) 3508 1D Compatibility (HY) -14800 + (ID) 4200 Total energy: -177634.0 ( -91.80 by residue) QMean score : 0.355

(partial model without unconserved sides chains): PDB file : Tito_2HXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HXQ-query.scw PDB file : Tito_Scwrl_2HXQ.pdb: