Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIILTTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAIAKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN 4YN8 Chain:A ((6-203)) -IRVMLIDDHPVVRAGLRSILDSFDDITVVAEASDGS----NINTKGIDVVVTDIQMPGTDGITLTRALANAGGPPVLILTTYDTEADILAAVEAGAMGYLLKDAPESALHDAVVATFEGRRTLAPEVANALMQ------RVSKPRQALSAREIEILQNLEQGLSNRQLAAKLFISEATVKTHLVHIYSKLGVDNRTAAITAARQQRLI----

General information: TITO was launched using: RESULT: Template: 4YN8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 906 -124434 -137.34 -628.45 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -137.34 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.620

(partial model without unconserved sides chains): PDB file : Tito_4YN8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YN8-query.scw PDB file : Tito_Scwrl_4YN8.pdb: