Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)



Input alignment information:
Query sequenceMSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCA-THPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKI-DQGDLM-TPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDSVYIHDHENGAEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQEAWKYNRECKLLRDTLQSFSWNGRGFTDKVDRLKLAEIVKQVIEEQTTSHESQ
2YCS Chain:A ((7-278))--------------ALRDEYIMSKT--LGS---GEVKLAFERKTCKKVAIKIISK----NVETEIEILKKLNHPCIIKIKNFFDAEDYY-----------IVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKIL--TSLMRTLCGTPTYLAPEVL---------------VSVGTAGYNRAVDCWSLGVILFICLSGYPPF-SEHRTQVSLKD---QITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------


General information:
TITO was launched using:
RESULT:

Template: 2YCS.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
3D Compatibility (PKB) -156476 for 1818 contacts (-86.1/contact) +
2D Compatibility (PS) -26680 + (NN) -13930 + (LL) 15736
1D Compatibility (HY) -22000 + (ID) 5100
Total energy: -208450.0 ( -114.66 by residue)
QMean score : 0.519

(partial model without unconserved sides chains):
PDB file : Tito_2YCS.pdb:





(Unconserved sides chains are recalculated) :
Sequence: align-2YCS-query.scw
PDB file : Tito_Scwrl_2YCS.pdb: