Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGAL----LHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERD------QEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP 4CZU Chain:B ((12-269)) ------------------------------KYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIA-QIKREISTMKLIK------HPNVIRMFEVMASKTKIYFVLE-FVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA-NGALKVSDFGLSALPQQVREDGLLHDTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFEDDVDAIFDDSG----

General information: TITO was launched using: RESULT: Template: 4CZU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -174197 for 1942 contacts (-89.7/contact) + 2D Compatibility (PS) -26218 + (NN) -9343 + (LL) -256 1D Compatibility (HY) -23200 + (ID) 4500 Total energy: -237714.0 ( -122.41 by residue) QMean score : 0.426

(partial model without unconserved sides chains): PDB file : Tito_4CZU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CZU-query.scw PDB file : Tito_Scwrl_4CZU.pdb: