Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTILAIDTSNYTLGIALLREDTVIAEYITYLKKNHSVRAMP-AVHSLLNDCDMAPQDLSKIVVAKGPGSYTGVRIGVTLAKTLAWSLDIPIS-AVSSLETLAANG---RHFDGLISPIFDAR-RGQVYTGLYQYKNGLLEQVVPDQNVMLADWLEMLKEKDRPVLFLGHDTSLHKQMIEDVLGTKGFIGTAAQHNPRPSELAFLGKEKEAADVHGLVPDYLRLAEAEAKWIESQK 3ZEU Chain:A ((3-128)) --ILAIDTATEACSVALWNNGTINAHF-ELCPREHTQRILPM-VQEILAASGASLNEIDALAFGRGPGSFTGVRIGIGIAQGLALGANLPM-IGVSTLATM-AQGAWRKTGATRVLAAIDARM-GEVYWAEYQ------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3ZEU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 521 -82758 -158.84 -689.65 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -158.84 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_3ZEU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZEU-query.scw PDB file : Tito_Scwrl_3ZEU.pdb: