Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIDYVSDLHINHWIPWNV---NQ-----------IKWEKRTREIVNRLISNGNGEVLVIAGDFTEWNQ--QTLWVLDEAAKQ---YEKVYFTYGNHDLYLLSKSQK-RK-----YSDSLGRLNDLIQKAADMKNVT-----PLIKTTETYKGKVFAGDVMWYLPKGIEGWDFFKGVSNDSNYIWLNGYNKVDGVRAMWKESMDW-YETLE----NTQVDVFVSHVPPVHNPYSPF-EP----NTCYMVDVPFINAKHWVCGHDHLQAEFDKDGTSFHMNCIGYPYDYDNYPSVNVIPGEEVDSYKTFELKTFEI 2XMO Chain:A ((40-290)) LSMVVTTDVHYFAPSLTDNGKAFEKYVAAGDGKQLAYSDEITDAFLADVE-SKKTDVLIISGDLTNNGEKTSHEELAKKLTQVEKNGTQVFVVPGNHDINNPWARKFEKDKQLPTDTISPTDFSKIYSDFG-YEDAISSDEFSLSYLAAPSSKVWLLMLDTAIYKTNMQQ---------------GNP----TTEGGLTAGTLDWIKESSALAKKNGAKLIPVLHHNLTDHNDV--KGYTINYNQQVIDALTEGAMDFSLSGHIHTQNIRSA-------------------------------------------

General information: TITO was launched using: RESULT: Template: 2XMO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1072 24944 23.27 119.35 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 23.27 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.392

(partial model without unconserved sides chains): PDB file : Tito_2XMO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XMO-query.scw PDB file : Tito_Scwrl_2XMO.pdb: