Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEARNQTAISKFLLLGLIEDPELQPVLFSLFLSMYLVTILGNLLILLAVISDSHLHTPMYFFLSNLSFLDICLSTTTIPKMLVNIQAQNRSITYSGCLTQICFVLFFAGLENCLLAAMAYDRYVAICHPLRYT-VIMNPRLCGLLILLSLLTSVVNALLLSLMVLRLSFCTDLEIPLFFCELAQVIQLTC--SDTLINNILIYFA--ACIFGGVPLSGIILSYTQITSCVLR---------MPSASGK---HKAVSTCGSHLSIVLLFYGAGLGVYISSVVT------DSPRKTAVASVMYSVFPQMVNPFIYSLRNKDMKGTLRKFIGRIPSLLWCAICFGFRFLE 4UHR Chain:A ((8-303)) -------------------------VYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIG---LTPM-LGWNNCGQPKEGKA---GCGEGQVACLFEDVVPMNYMVYFNFFACVL--VPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAAA---

General information: TITO was launched using: RESULT: Template: 4UHR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -283263 for 2123 contacts (-133.4/contact) + 2D Compatibility (PS) -26435 + (NN) 2535 + (LL) 2940 1D Compatibility (HY) -24000 + (ID) 4000 Total energy: -332223.0 ( -156.49 by residue) QMean score : 0.345

(partial model without unconserved sides chains): PDB file : Tito_4UHR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UHR-query.scw PDB file : Tito_Scwrl_4UHR.pdb: