Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD 4AN3 Chain:A ((5-281)) ----------------------------------------------ELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLD----QVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDEMANE---GTRSYMSPER----LQGTHYSVQSDIWSMGLSLVEMAVGRYPRPPMAI-FELLDYIVNEPPPKLPSAVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGL

General information: TITO was launched using: RESULT: Template: 4AN3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -178099 for 2233 contacts (-79.8/contact) + 2D Compatibility (PS) -29121 + (NN) -12028 + (LL) 1924 1D Compatibility (HY) -28000 + (ID) 6050 Total energy: -251374.0 ( -112.57 by residue) QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_4AN3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AN3-query.scw PDB file : Tito_Scwrl_4AN3.pdb: