Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKITISKVLPDFETLVVGLFEDGELVSNGKVLQDKQIINSIKKFSHFNGGFGEFFSVTLSDGKNVIIVGLGKR-------DEWNENKE-LSVGGKIYC-ELGRLKIKQATVSIEGSAENIAYGAFLRSFKFDKYKTKKDEEITEVEEIMVLAKDEQLNDAEKSFEHLRQEGEGIFLARTFITEPPNVLYPESYADCIKSELTKFGLEIEVL--DKKQMEKKKMGALLGVAQGSSKEPKLVVIRWNGA-SKEQKPIAFVGKGITFDTGGVSLKPSRGMESMKYDMAGSAAVVGVMRTLAGRKARINAVGVVALAENAIDGNAQRPSDVVTSMSGQTIEVLNTDAEGRLVLADALWYTQDRFAPEFMIDLATLTGAIVVALGNNEYAGLFSNNDELANRLVEAGNEANEKLWRFPMNETYDK-IIDSPIADVQNIAPTGSGGDSIMAAQFLQRFVNDTCWAHLDIAGTAWHEKGTDISPKGAVGFGVRLLNKLVEKYYETSD 2EWB Chain:A ((60-486)) -------------------------------------------------------------DFPSVVVVGLGKKTAGIDEQENWHEGKENIRAAVAAGCRQIQDLEIPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKR--------KVVVSAKLHGSEDQE-AWQRGVLFASGQNLARRLMETPANEMTPTKFAEIVEENLKSASIKTDVFIRPKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYKGSPNASEPPLVFVGKGITFDSGGISIKAAANMDLMRADMGGAATICSAIVSAAKLDLPINIVGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHT-FNPKVIINAATLTGAMDIALGSGA-TGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVIDCQLADVNNIGKYRSAG-ACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMAGRPTRTLIEFLFRFSQDS-

General information: TITO was launched using: RESULT: Template: 2EWB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -180048 for 3985 contacts (-45.2/contact) + 2D Compatibility (PS) -44664 + (NN) -21626 + (LL) 4892 1D Compatibility (HY) -28400 + (ID) 7900 Total energy: -277746.0 ( -69.70 by residue) QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_2EWB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2EWB-query.scw PDB file : Tito_Scwrl_2EWB.pdb: