Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNA----VRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEE---KWIDKMEQLSVAALLGEAIVRVHENASVSSLFE 2H08 Chain:A ((3-313)) --------NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLMAEPAVLKWIRENISEWR---NCTIVSPDAGGAKRVTSIADRLNVDFALIHKER------DRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTI--PQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLF-

General information: TITO was launched using: RESULT: Template: 2H08.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -280221 for 2502 contacts (-112.0/contact) + 2D Compatibility (PS) -33432 + (NN) -24810 + (LL) 640 1D Compatibility (HY) -30800 + (ID) 7300 Total energy: -375923.0 ( -150.25 by residue) QMean score : 0.601

(partial model without unconserved sides chains): PDB file : Tito_2H08.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H08-query.scw PDB file : Tito_Scwrl_2H08.pdb: