Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDKLSQEQIDALLSQMSEGKVVDESTEIGDF-----GRFHPYDFHKPEKFGAEHLESLKT-IASAFTKKSMEFVSQRIRIPIHTEATLADQVSFASGYIETMPNDSYIFCIIDLGNPELGQIIIELDLAYIIYIHECLSGGNPKRKLSERRLLSVFEELTLKSILEKFCEALKDSFKSVHPISPEIVNIETNPALLRVTSPNDMMALVSVDIKSEFWISTMRIGVPFFSVEEIMNKLENVVEYTFDKRRNFDAEVEQELHQVEKEARIRVGEIKTTWKELNKLEVGDVLLTETHIRDTLKGYVTEKWKFECYMGKSGNQKAVKFMRHTGRTEQER 3VH3 Chain:A ((227-323)) MASSLAVELMTSLLQTKYSGS---ETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEI--SGLSVIKQEVER------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3VH3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 7829 for 467 contacts (16.8/contact) + 2D Compatibility (PS) -9182 + (NN) 2470 + (LL) 18884 1D Compatibility (HY) -7200 + (ID) 1300 Total energy: 11501.0 ( 24.63 by residue) QMean score : 0.148

(partial model without unconserved sides chains): PDB file : Tito_3VH3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3VH3-query.scw PDB file : Tito_Scwrl_3VH3.pdb: