Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METVLQAKNVRKIYGSKGNVYTALENISIDIKEGEFTGIMGPSGAGKSTLLNVLSTIDKPTSGQIVISGQELENMNEQQMSTFRRDKLGFIFQDYNLLDTLTIRENIIL-PLALAKRPVKEMEEKLAIISEKFGITEILDKYPSEISGGQKQRTAASRAIITSPSLIFADEPTGALDSKSATNLLESLRDLNEQDKSTIMMVTHD-AFAASFCKRILFIKDGELYTE------IYRGTKTR-KEFFQKILDVLAKLGGDSDDVI 4U00 Chain:A ((3-242)) --PIIRIRNLHKWFGP----LHVLKGIHLEVAPGEKLVIIGPSGSGKSTLIRTINRLEDFQEGEVVVDG--LSVKDDRALREIRRE-VGMVFQQFNLFPHMTVLENVTLAPMRVRRWPREKAEKKALELLERVGILDQARKYPAQLSGGQQQRVAIARALAMEPKIMLFDEPTSALDPEMVGEVLDVMRDLA-QGGMTMVVVTHEMGFAREVADRVVFMDGGQIVEEGRPEEIFTRPKEERTRSFLQRVL--------------

General information: TITO was launched using: RESULT: Template: 4U00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -102656 for 1880 contacts (-54.6/contact) + 2D Compatibility (PS) -25269 + (NN) -11186 + (LL) 1180 1D Compatibility (HY) -21200 + (ID) 3950 Total energy: -163081.0 ( -86.75 by residue) QMean score : 0.448

(partial model without unconserved sides chains): PDB file : Tito_4U00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U00-query.scw PDB file : Tito_Scwrl_4U00.pdb: