Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKKWLAGILLIMLVGYTGWNLYQTYSKKEVGIQEGQQAPDFSLKTLSGEKSSLQDAKGKKVLLNFWATWCKPCRQEMPAMEKLQKEYADK-LAVVAVNFTSAEKSEKQVRAFADTYDLTFPILIDK-KGINADYNVMSYPTTYILDEKGVIQDIHVGTMTKKEMEQKLDLD 3C73 Chain:A ((3-132)) --------------------------------------APNFVLEDTNGKRIELSDLKGKGVFLNFWGTWCEHCKKEFPYMANQYKHFKSQGVEIVAVN---VGESKIAVHNFMKSYGVNFPVVLDTDRQVLDAYDVSPLPTTFLINPEGKVVKVVTGTMTESMIHDYMNL-

General information: TITO was launched using: RESULT: Template: 3C73.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 592 -23555 -39.79 -184.02 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -39.79 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.697

(partial model without unconserved sides chains): PDB file : Tito_3C73.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C73-query.scw PDB file : Tito_Scwrl_3C73.pdb: