Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYRTMMSGKLHRATVTEANLNYVGSITIDEDLIDAVGMLPNEKVQIVNNNNGARLETYIIPGKRGSGVICLNGAAARLVQEGDKVIIISYKMMSDQEAASHEPKVAVLNDQNKIEQMLGNEPARTIL 3PLX Chain:B ((4-101)) -------------------------ISIDEKLLQASGILEYEKVQVVNVNNGARFETYTIATQE-EGVVCLNGAAARLAEVGDKVIIMSYADFNEEEAKTFKPKVVFVDENNTATKITNYEKHGAI-

General information: TITO was launched using: RESULT: Template: 3PLX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 332 14342 43.20 146.34 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : 43.20 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.029

(partial model without unconserved sides chains): PDB file : Tito_3PLX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PLX-query.scw PDB file : Tito_Scwrl_3PLX.pdb: