Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEAVAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDPIFIVKDKDKTMAELTSDEKNKISHRADALKKLSKLLEA 2DVP Chain:A ((4-182)) -------FFITSNPGKVREVANFLGTFGIEIVQLKH----EYPEIQAEKLEDVVDFGISWLKGKVPEPFMIEDSGLFIESLKGFPGVYSSYVY-----RTIGLEGILKLMEG--AEDRRAYFKSVIGFYIDGKAYK-FSGVTWGRISNEKRGTHGFGYDPIFIPEGSEKTFAEMTIEEKNALSHRGKALKAFFEWLKV

General information: TITO was launched using: RESULT: Template: 2DVP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 931 -53174 -57.11 -297.06 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -57.11 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_2DVP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2DVP-query.scw PDB file : Tito_Scwrl_2DVP.pdb: