Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKKVIVLGEIRDGELRNVTFEAIAA--GRTISGDGEVIGVLIGENVQSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLSPKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERV-ISTDPMIFATIRPNNIQASEKDTSRSGSIESIDVSLTDLRTVIQEVVK-KTADGVDLSEAKIIVAGGRGVKSKEGFQPLQELAEVLGAAVGASRGACDADYCDYALQIGQTGKVV-TPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS 1O97 Chain:D ((2-315)) ---KILVIAEHRRNDLRPVSLELIGAANGLKKSGEDKVVVAVIGSQADAFVPALSVNGVDELVVVKGSSID-FDPDVFEASVSALIAAHNPSVVLLPHSVDSLGYASSLASKTGYGFATDVYIVEYQGDELVATRGGYNQKVNVEVDFPGKSTVVLTIRPSVFKPLEG--AGSPVVSNVDAPSVQSRSQNKDYVEVG---DIDITTVDFIMSIGRGIGEETNVEQFRELADEAGATLCCSRPIADAGWLPKSRQVGQSGKVVGSCKLYVAMGISGSIQHMAGMKHVPTIIAVNTDPGASIFTIAKYGIVADIFDI----EEELK------

General information: TITO was launched using: RESULT: Template: 1O97.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1677 -337 -0.20 -1.10 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain D : 0.79 3D Compatibility (PKB) : -0.20 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.562

(partial model without unconserved sides chains): PDB file : Tito_1O97.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1O97-query.scw PDB file : Tito_Scwrl_1O97.pdb: