Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDQRRNVYFFHKQDQETNEQARSLTQLAEEHGFTVVNQHSDANIIASIGGDGTFLQAVRKTNFR-DDCLYVGITKKGKAHLYCDFHSDEREKMVDAMTFEQIEVRKYPLIEVTVD--QASPFHCLNEVSIRSSIIKTFVMDVLIDDLHFETFRGDGMIISTPTGSTAYNKSVAGAVVDPLLPCMQVSELASLNNNTYRTLGSPFVLSSDRKLTLRVVQDGNEHPIIGLDNEALSTRNVKTIEIKLSNKKIKTVKLKDNSFWEKVKRTFL 3V80 Chain:A ((35-262)) -----------------------------------------EPEIVISIGGDGTFLSAFHQYEERLDEIAFIGI-HTGHLGFYADWRPAEADKLVKLLA---YQKVSYPLLKTTVKYGKEATYLALNESTVKSSG-GPFVVDVVINDIHFERFRGDGLCMSTPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIGSPLVFPKHHVVSLQPVNDKDFQ--ISVDHLSILHRDVQEIRYEVSAKKIHFARFRSFPFWRRVHDSFI

General information: TITO was launched using: RESULT: Template: 3V80.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1168 29942 25.63 136.72 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : 25.63 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_3V80.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V80-query.scw PDB file : Tito_Scwrl_3V80.pdb: