Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEWNKTKSIFIVAFLILDIFLGYQFFQKWQATGKEYEVIKNDVEHDMKADHITYEGLNKEATEGYRITANQKSFSKEEIEALKDQKPLMDMPSDDHKVTSLKMKFANPIALSKKDIEDDAQALVSSKIQDGEKYKLWKVD--KSK-KEIIFFQTYEGHYIYQKTDNPSNMIGQVVLHLNGKNEVVSYDQTTLETFKQI--QKESLITEMDAVELLYYQNQ----LKEYSTVKSCKFGYVAQYPLTSTQVLAPVWRITVEYEKKVNGEKKTVQEYFTVNALESTILDTDQ 3NQZ Chain:A ((38-175)) -----------------------------------------------------------------------------------------------------------------------------------NELVVLKEFTSNNGEVTRRYQQTYQGIPVIG---------DTVSLTFN-NGMLKKAHGAAVYNIDEDLSDVSAKLTKKDAILKGSKTGIAAKSVGLKKHNEQSRLAIWVDD----QNKAHLVYEVSYVTYGKSPS--R---PYLIIDANTGEVLLSY-

General information: TITO was launched using: RESULT: Template: 3NQZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 511 17105 33.47 132.60 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 33.47 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_3NQZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NQZ-query.scw PDB file : Tito_Scwrl_3NQZ.pdb: