Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLKDIISACDLAIQNEDFDTLMNYYSEDAV--LVVKPGMIARGKEEIKKAFITIANYFNHHIVPTQGKMILLEAGDTVLVLSQTLLDSDKKDSEYAMERRATYVFKKNAQGEWLCVIDNSYGTDLIGV 3GWR Chain:A ((7-129)) -FPTPEAAEDAFYAAFEARSLDDMMAVWARDDHVACIHPLAAPLNGRAAVAAGWRSMFGAA-GRFRLQVKAVHEIRQADHVIRIVDEFLTIG-DETAPRPAILATNVYRRE-ADGWRMVLHHASPLQ----

General information: TITO was launched using: RESULT: Template: 3GWR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 526 -17936 -34.10 -148.23 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -34.10 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.351

(partial model without unconserved sides chains): PDB file : Tito_3GWR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GWR-query.scw PDB file : Tito_Scwrl_3GWR.pdb: