Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHPTPRLAAALLAGSGLGWPLLAQADLVEDSHASLELRNFYFNRDFRQSGARDNADEWAQGFLLRLESGFSEGTVGFGVDAIGLLGFKLDSGSGSGGTGLLPADG------SAGGSQDDYAKLGLTAKARVSNSLLKVGALHFKSPLVSANDTRLLPELFRGALLDVQEIDGLTLRGAHLDRNKLNSSSDYQVFSANRIGGR------SDAFDFAGGDYRLTPALTASLHQGRLKDIYRQTFAGLVHTLDLGGQRSLKSDLRFARASEDG--GFR--------------------ELDNRAFGALFSLRLGAHAVAAGYQRISGDDPYPYI-----AGSDPYLVNFIQIGDFGNVDERSWQLRYDYDFGALGLPGLSFMSRYVSGDNVARGAANDGKEWERNTDLGYVVQSGPLKNLGVKWRNATVR--SNFANDLDENRLILSYSLALW 4FRX Chain:A ((7-436)) ------------------------AGFIEDSKASLTLRNFYINTDNR-----SKQEEWGQGFILNYQSGFTQGTVGFGVDALGLLGVRL---------------GTVFPLESNGEPVHDFASLGLTAKAKVSNTEFRYGTLQPKLPVVTYNDGRLLPVTFEGGQVTSTDLKDFTLVAGQLEHSKGRNSTDNRSLSIAGANGSSASSRDSNKFYYAGGDYKVNKDLTLQYYYGNLDDFYKQHFLGLIHNWQI-GPGVLKTDLRAFDSSSDGKNGSRSGRADGYVSSGYYGSGVTKGEVDNRAFSGLFTYTVSGHSIGAGYQILNGDSDFPFLNRGDGEGSTAYLITDVQIGKFQRAGERTWQVRYGYDFATVGVPGLTFNTIYLSGDKI-KTARGDQSEWERDISLAYVIPDGTFKGLGFTWKNASFRSG-----DQDENRLIVSYTLPLL

General information: TITO was launched using: RESULT: Template: 4FRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -15904 for 2725 contacts (-5.8/contact) + 2D Compatibility (PS) -36048 + (NN) 1462 + (LL) 1028 1D Compatibility (HY) -34000 + (ID) 8650 Total energy: -92112.0 ( -33.80 by residue) QMean score : 0.215

(partial model without unconserved sides chains): PDB file : Tito_4FRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FRX-query.scw PDB file : Tito_Scwrl_4FRX.pdb: