Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVEPDVETLDPPLPPVPDGAVMVTVKIARFNPD-DPDAFAATGGWQSFRVPCLP-SDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVEPIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPP--TRERIQSPTDRARYDDTTKCILCACCTTSCPVFWHEG-SYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTESCPRGIEVTKAIQEVKRALMFTR 2H88 Chain:B ((8-245)) -------------------TSRIKKFSIYRWDPDKPGDK----PRMQTYEVDLNKCGPMVLDALIKIKNELDSTLTFRRSCREGICGSCAMNIAGGNTLACTKKIDPDL------SKTTKIYPLPHMYVVKDLVPDLSNFYAQYKSIEPYLKKKDESKQGKEQYLQSIEDRQKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDYTEERLAQLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATY-

General information: TITO was launched using: RESULT: Template: 2H88.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -143389 for 1748 contacts (-82.0/contact) + 2D Compatibility (PS) -25277 + (NN) -15911 + (LL) 816 1D Compatibility (HY) -19200 + (ID) 4800 Total energy: -207761.0 ( -118.86 by residue) QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_2H88.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H88-query.scw PDB file : Tito_Scwrl_2H88.pdb: