Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSKGVESRKRLLKAAANEFSVRGFHDAKVSEIVKKAGFTQPSFYLYFQSKEAIFAELITDFHSRVRKLTESLLLENGLNTEDVSKRVLLAVETVFQFLDEDKDLTKIGFF----------LNPEAKQMKKDLAMVLKENLEAEQRLGYFHSELDMETVAECLVGMIEHLTESFLLTGIK-DPASLAAEVVNLLIYGMLPKGNDVR 2UXU Chain:A ((5-210)) TKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHFNNKAELVQALLDSLHETHDHLARASESEDEVDPLGCMRKLLLQVFNELVLDARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDCHKGITLALANAVRRGQLPGELDAERAAVAMFAYVDGLIRRWLLLPDSVDLLGDVEKWVDTGLDMLRLSPALRK

General information: TITO was launched using: RESULT: Template: 2UXU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 718 -92321 -128.58 -473.44 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -128.58 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_2UXU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2UXU-query.scw PDB file : Tito_Scwrl_2UXU.pdb: