Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNEMKEYIRQKIADCMEA-CTDPAEGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKLRQT----GC-SESRAKEASTVVNAMIEGGILLSLTAKNSTPLLHISSCIPDLLKR 4YZE Chain:A ((7-193)) ---HDTREHLLATGEQLSLQRGFTGMGLSELLKTAEVPKGSFYHYFR-SKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFSQHGTISGCLTVKLSAEVSDLSEDMRSAMDKGARGVIALLSQALENGRENHSLTFSGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAHVKNI---

General information: TITO was launched using: RESULT: Template: 4YZE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 658 -75267 -114.39 -415.84 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -114.39 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_4YZE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YZE-query.scw PDB file : Tito_Scwrl_4YZE.pdb: