Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVVGDFPIETDTLVIGAGPGGYVAAIRAAQLGQKVTVVEKAT-LGGVCLNVGCIPSKALINAGHRYENAKHSDD---MGITAENVTVDFTKVQEWKASVVNKLTGGVAGLLK--GNKVDVVKGEAYFVD---------SNSVRVMDENSAQTYTFKNAIIATGSRPIELPNFKYSER-----VLNSTGALALKEI--PKKLVVIGGGYIGTELGTAYANFGTELVILEGGDEILPGFEKQMSSLVTRRLKKKGNVEIHTNAMAKGVEERPDGVTVTFEVKG---EEKTVDADYVLITVGRRPNTDELGLEQVGIEMTDRGIVKTDKQCRTNVPNIYAIGDIIEGP-PLAHKASYEGKIAAEAIAGEPAE-----IDYLGIPAVVFSEPELASVGYTEAQAKEEGLDIVAAKFPFAANGRALSLNETDGFMKLITRKEDGLVIGAQIAGAS-ASDMISELSLAIEGGMTAEDIAMTIHAHP---TLGEITMEAAEVAIGSPIHIVK 1EBD Chain:A ((1-455)) ------AIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKG-NLGGVCLNVGCIPSKALISASHRYEQAKH-SEEMGIKAE--NVTIDFAKVQEWKASVVKKLTGGVEGLLKGNK-VEIVK-GEAYFV-DANTVRVVN--------GDSAQTYTFKNAIIATGSRPIELPNFKFS--NRILD---STGALNLG--EVPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKG-VEVVTNALAKGAEERE-DGVTVTYEANGET-KTID-ADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQCRTSVPNIFAIGDIVPG-PALAHKASYEGKVAAEAIAG----HPSAVDYVAIPAVVFSD-PECASVGYFEQQAKDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIG-PNASDMIAELGLAIEAGMTAEDIALT--IHAHPT-LGEIAMEAAEVAL--------

General information: TITO was launched using: RESULT: Template: 1EBD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2413 -286447 -118.71 -682.02 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : -118.71 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_1EBD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EBD-query.scw PDB file : Tito_Scwrl_1EBD.pdb: