Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIYPYKEHKPDIHPTAFIADNATITGDVVIGEQSSIWFSVVIRGDVAPTRIGNRVNIQDLSCLHQSPNKTLLIEDDATIGHQVTLHSAVIRKNALIGMGSIILDGAEIGEGAFIGAGSLVPPGKIIPPGHLAFGRPAKVIRPLTEEDRKDMQRIRSEYVEKGQYYKFLQQT 3IXC Chain:A ((31-191)) ------GVSPSVDSTAFIAGNARIIGDVCIGKNASIWYGTVLRGDVDKIEVGEGTNIQDNTVVHT---GDTVIGKFVTIGHSCILHACTLGNNAFVGMGSIVMDRAVMEEGSMLAAGSLLTRGKIVKSGELWAGRPAKFLRMMTEEEILYLQKSAENYIALSRGYL-----

General information: TITO was launched using: RESULT: Template: 3IXC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 960 -118502 -123.44 -754.79 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -123.44 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.553

(partial model without unconserved sides chains): PDB file : Tito_3IXC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IXC-query.scw PDB file : Tito_Scwrl_3IXC.pdb: