Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MARPLAMIAALGENRAIGIDNRLPWRLPADLKHFKAMTLG-------KPVIMGRKTWDSLG---RPLPGRLNLVVSRQAGLA--LEGAEVFASLDAALARAEAWAQAEDADELMLIGGAQLYAEAL--PRAARLYLTRVGLA----PEGDAFFPEIDGAAWRLASSIEH----------AAADDA-PAYAFEVWERR 1AOE Chain:A ((6-192)) ---VAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVS------DVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKF-PLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK

General information: TITO was launched using: RESULT: Template: 1AOE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -91086 for 1131 contacts (-80.5/contact) + 2D Compatibility (PS) -16952 + (NN) -3089 + (LL) 1468 1D Compatibility (HY) -12800 + (ID) 2450 Total energy: -124909.0 ( -110.44 by residue) QMean score : 0.489

(partial model without unconserved sides chains): PDB file : Tito_1AOE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AOE-query.scw PDB file : Tito_Scwrl_1AOE.pdb: