Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METFKSILHEAQRIVVLTGAGMSTESGIPDFRSAGGIWTEDASRMEAMSLDYFLSYPRLFWPKFKELFQMKMSGSFEPNEGHLLLAELEKQGKQVDIFTQNIDGLHKKAGSRHVYELHGSIQTAACPACGARYD-LPHL----LEREVPECTAAGNNGDICGTVLKTDVVLFGDAVMH--FDTLYEKLDQADLLLVIGTSLEVAPARFVPEDASLIPGMKKVIINLEPTYCDSLFDMVIHQKIGEFARSLGMKK 1YC5 Chain:A ((3-241)) MKEFLDLLNESRLTVTLTGAGISTPSGIPDF-------------QNVFDIDFFYSHPEEFYRFAKEGIFP--MLQAKPNLAHVLLAKLEEKGLIEAVITQNIDRLHQRAGSKKVIELHGNVEEYYCVRCEKKYTVEDVIKKLESS-DVPLC-D------DCNSLIRPNIVFFGENLPQDALREAIGLSSRASLMIVLGSSLVVYPAAELPLITV-RSGGKLVIVNLGETPFDDIATLKYNMDVVEFARRVME--

General information: TITO was launched using: RESULT: Template: 1YC5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1205 -155507 -129.05 -703.65 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -129.05 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.472

(partial model without unconserved sides chains): PDB file : Tito_1YC5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YC5-query.scw PDB file : Tito_Scwrl_1YC5.pdb: