Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSISCSKEYAEDVRNLNIRPEQLDDFFGQKDLIQNLKVFINAAKTRTEALDHVLLHGPPGLGKTTLAQIISKELRVSFRATSGPLLNKAGDLAAVLTT-LNAKDVLFIDEIHRLNRSIEEVLYTAMEDFCLDLLVGEGPSTRTLRIDLPPFTLVGATTRLGLLSAPLRDRFGIPLRLEFYSFEELVDIIKRGTKVFSAEIEEDAIQEIACRARGTPRIALRLLRRIRDFVEVKDNKKITHKIADSALSKLGIDKMGLNKLDVDYLRFLFN--TSGSVGIDTISIALSEDSGNIEETVEPYLVKISFVKRTPRGRVLTDQGKEYLSLQY 1HQC Chain:A ((5-316)) -----------------ALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAILANSLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITAPLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGTMRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREILEVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRVPTELAYRHLGYPP

General information: TITO was launched using: RESULT: Template: 1HQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -194560 for 2482 contacts (-78.4/contact) + 2D Compatibility (PS) -32879 + (NN) -9116 + (LL) 1304 1D Compatibility (HY) -27200 + (ID) 7950 Total energy: -270401.0 ( -108.94 by residue) QMean score : 0.396

(partial model without unconserved sides chains): PDB file : Tito_1HQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HQC-query.scw PDB file : Tito_Scwrl_1HQC.pdb: