Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATEYDVVILGGGTGGYVAAIRAAQLGLKTAVVEKEK-LGGTCLHKGCIPSKALLRSAEVYRTAREADQ---FGVETAGVSLNFEKVQQRKQAVVDKLAAGVNHLMKK-GKIDVYTGYGRILGPSIFSPLPGTISVERGNGEENDMLIPKQVIIATGSRPRMLPGLEVDG---KSVLTSDEALQMEEL--PQSIIIVGGGVIGIEWASMLHDFGVKVTVIEYADRILPTE-DLEISKEMESLLKKKGIQFITGAKVLPDTMTKTS-DDISIQAEKDGE---TVTYSAEKMLVSIGRQANIEGIGLENTDI-VTENGMISVNESCQTKESHIYAIGDVIGGL-QLAHVASHEGIIAVEHFAGLNPHPLDPTLVPKCIYS-SPEAASVGLTEDEAKANGHNVKIGKFPFMAIGKALVYGESDG----FVKIVADRDTDDILGVHMIGPHVTDMISEAGLAKVLDATPWEVGQT--IHPHPTLSEAIGEAALAADGKAIHF 1EBD Chain:A ((1-455)) -AIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKG-NLGGVCLNVGCIPSKALISASHRYEQAKH-SEEMGIKAE--NVTIDFAKVQEWKASVVKKLTGGVEGLLKGNK-VEIVK-GEAYFV-DA-N--TVRVVN----GDSAQTYTFKNAIIATGSRPIELPNFKFS-NRILD---STGALNLG--EVPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILSG-FEKQMAAIIKKRLKKKGVEVVTNALAKGAEERE-DGVTVTYEAN----GETKTID-ADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQCRTSVPNIFAIGDIVPG-PALAHKASYEGKVAAEAIAG-HPSAVDYVAIPAVVFSD-PECASVGYFEQQAKDEG----IDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPT--LGEIAMEAAEVAL------

General information: TITO was launched using: RESULT: Template: 1EBD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2493 3663 1.47 8.50 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 1.47 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.528

(partial model without unconserved sides chains): PDB file : Tito_1EBD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EBD-query.scw PDB file : Tito_Scwrl_1EBD.pdb: