Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNEMKEYIRQKIADCMEACTDPAEGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKL----RQTGC-SESRAKEASTVVNAMIEGGILLSLTAKNSTPLLHISSCIPDLLKR 2G7S Chain:A ((3-190)) -NPQSKADDILQCARTLIIRGGYNSFSYADISQVVGIRNASIHHHFP-SKSDLVCKLVSQYRQEAEAGIAELEKNISDPLEQLRAYIGYWEGCIADAT-HPFCVCALLASEIPVLPETVVLEVRAHFRSLSDWLTAVLERGIAQGRLVLTGTARANAEIFMATVHGAMLSARAHGDAATFGAITRP-LERI--

General information: TITO was launched using: RESULT: Template: 2G7S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 675 -94674 -140.26 -520.18 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -140.26 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.409

(partial model without unconserved sides chains): PDB file : Tito_2G7S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2G7S-query.scw PDB file : Tito_Scwrl_2G7S.pdb: