Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIRHFLRDDDLSPAEQAEVLELAAELKKDP--V-SRRPLQGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGLDRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKALLVWLLERS 1PVV Chain:A ((6-312)) AGRDLLCLQDYTAEEIWTILETAKMFKIWQKIGKPHRLLEG-KTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYATVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGN-NVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDQAENRLHAQKAVLALVMGG-

General information: TITO was launched using: RESULT: Template: 1PVV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -181843 for 2736 contacts (-66.5/contact) + 2D Compatibility (PS) -33430 + (NN) -22765 + (LL) -248 1D Compatibility (HY) -26400 + (ID) 7450 Total energy: -272136.0 ( -99.46 by residue) QMean score : 0.600

(partial model without unconserved sides chains): PDB file : Tito_1PVV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PVV-query.scw PDB file : Tito_Scwrl_1PVV.pdb: