Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPQTEQIHQHSVLRDIIRSRRSIRKFKQEPVPSAVILDMLETAKYAPNHRVTEPWRFIYVSSETGKANLINTFAAFSKKSKPDMTEEKLQNFKNTLGRVPGFLLVVFQEDENERARDDDFAATSSLIQNLQLLAWEKGIGMVWKSGKILYDKEVHQAFGLQDNERFAAIIQTGYPDEAPEVKKRTPIRDRFTEM 2I7H Chain:A ((4-187)) ------MTTYTSIANVIKERRSVRTFTDKAVEKDLLIELLNDATWAPNHKHREPWNCKLYIGE-GRKKLVDAVLNSFTEE--E-RAKRGKILSDRFLSTPAQIVVYMNEDPRQIQRDEDYAATCAFMQNFQLLAWERGLGCVWKSGGLNYNPLFIEGIGLTRGQRIVGILHIGYFDKAPEGKARTPITEKMEII

General information: TITO was launched using: RESULT: Template: 2I7H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 734 -90439 -123.21 -491.51 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -123.21 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.583

(partial model without unconserved sides chains): PDB file : Tito_2I7H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I7H-query.scw PDB file : Tito_Scwrl_2I7H.pdb: