Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADEL-----SGLFVPTDVCDEDAVNGLFDGAAETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPE-RAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL 4FN4 Chain:A ((2-252)) ----YQSLKNKVVIVTGAGSGIGRAIAKKFALNDSIVVAVELLEDRLNQIVQELRGMGKEVLGVKADVSKKKDVEEFVRRTFETYSRIDVLCNNAGIMDG-VTPVAEVSDELWERVLAVNLYSAFYSSRAVIPIMLKQGKGVIVNTASIAGIRGG-FAGAPYTVAKHGLIGLTRSIAAHYGDQGIRAVAVLPGTVKTNIGLGSSKPSELGMRTLTKLMSLSSRLAEPEDIANVIVFLASDEASFVNGDAVVVDGGLT-------

General information: TITO was launched using: RESULT: Template: 4FN4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -105805 for 2235 contacts (-47.3/contact) + 2D Compatibility (PS) -26464 + (NN) -10797 + (LL) 1252 1D Compatibility (HY) -14400 + (ID) 4050 Total energy: -160264.0 ( -71.71 by residue) QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_4FN4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FN4-query.scw PDB file : Tito_Scwrl_4FN4.pdb: