Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIFFIDNFD-SFSYNLVYELECLGYEVAVYQND-ID-P-SYLMGLMNEEPKTPLLFISPGPGNPNSS---------GNLLKIIAM-AKKKFPILGVCLGLQALAQSYGAKIIRSKEIVHGKATTIALK----KHAVFKGLGESMVVGRYHSLMASGLPKNLEVIAEHD-NIPMAIVNEEDKILAYQFHPESIMTLQGRALLEQSVGFLRELS 3L7N Chain:A ((1-185)) MRIHFILHETFEAPGAYLAWAALRGHDVSMTKVYRYEKLPKDID-------DFDMLILMGGPQSPSSTKKEFPYYDAQAEVKLIQKAAKSEKIIVGVCLGAQLMGVAYGADYLHSPKKEIGN-YLISLTEAGKMDSYLSDFSDDLLVGHWHGDMP-GLPDKAQVLAISQGCPRQIIKFG-PKQYAFQCHLEFTPELVAALIAQEDDLDTQSQT

General information: TITO was launched using: RESULT: Template: 3L7N.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -117746 for 1316 contacts (-89.5/contact) + 2D Compatibility (PS) -18251 + (NN) -10207 + (LL) 420 1D Compatibility (HY) -7600 + (ID) 2200 Total energy: -155584.0 ( -118.22 by residue) QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_3L7N.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3L7N-query.scw PDB file : Tito_Scwrl_3L7N.pdb: