Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHL---ADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARL----KTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL 2Y00 Chain:A ((48-285)) -----------------------------------------------------------------------------LFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKV----IICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVT---NRAYAIASSIISFYIPLLIM-------IFVALRVYREAKEQ----------SRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDL---VPDWLFVAFNWLGYANSAMNPIIYCRSPD

General information: TITO was launched using: RESULT: Template: 2Y00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -200777 for 1539 contacts (-130.5/contact) + 2D Compatibility (PS) -22109 + (NN) -6553 + (LL) 7584 1D Compatibility (HY) -24800 + (ID) 3200 Total energy: -249855.0 ( -162.35 by residue) QMean score : 0.255

(partial model without unconserved sides chains): PDB file : Tito_2Y00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y00-query.scw PDB file : Tito_Scwrl_2Y00.pdb: