Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQRVSYYEIAPEGMKIMMDMEKYTKQSSINRTTRELIKIRVSQMNGCAFCIDMHTSDARKMGETEQRIYCLHAWN--ECDFYSPEEKAALELSEHITLIPSKRVPDELYHRVREH-YDEEQYVDLVLIINQINSWNRISIAMGNRAASK 2PRR Chain:A ((65-182)) -------------------------KDGGLTKGEREMIVVATSAANQCLYCVVAHGAILR-IYEKKPLVADQVAVNYLKADI-PPRQRAMLDFALKVCKA-SHEVNEADFEALREHGFTDEDAWDIAAITAFFGLSNRMANTIGMR----

General information: TITO was launched using: RESULT: Template: 2PRR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 488 -56800 -116.39 -493.91 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -116.39 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.353

(partial model without unconserved sides chains): PDB file : Tito_2PRR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PRR-query.scw PDB file : Tito_Scwrl_2PRR.pdb: