Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSL-GGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVP-ESCDLRLCTLDPDDVASTTSSSESL 2OI4 Chain:X ((32-306)) ---------------------------------EPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--GFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM--QDVLLPQETAEIHLHS----------------

General information: TITO was launched using: RESULT: Template: 2OI4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -176805 for 2238 contacts (-79.0/contact) + 2D Compatibility (PS) -29141 + (NN) -13003 + (LL) 1984 1D Compatibility (HY) -39200 + (ID) 10000 Total energy: -266165.0 ( -118.93 by residue) QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_2OI4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OI4-query.scw PDB file : Tito_Scwrl_2OI4.pdb: