Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIE--DNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRR-VMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 2XKD Chain:A ((7-262)) --------------------------------DYEVLYTIGTG---RCQKIRRKSDGKILVWKELDYGSMTEAEKQM-LVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSD-----LKPANVFLDGKQNVKLGDF--------------TFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2XKD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -133276 for 1628 contacts (-81.9/contact) + 2D Compatibility (PS) -24765 + (NN) -16708 + (LL) 2412 1D Compatibility (HY) -22400 + (ID) 4300 Total energy: -199037.0 ( -122.26 by residue) QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_2XKD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XKD-query.scw PDB file : Tito_Scwrl_2XKD.pdb: