Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSFCVKAPAKINLFLHVVEKKETGYHLIEGLFVFANLSNFLEIKVGEKDFRYDNPIVEFVNSELKISNKYNTVMRAVNLLLRHAPVRTKVTVKVVKNIPTSAGLGSGSSDAGAVIRTLGKLWKIDRPI----LNEIALSVGADVPASIDSKPVLVRGIGEELCYINKFSLPTNIVLAKPKKKFLSTPEVFSKYG-GNFSKPIEWRDDTEKDLLKLLKETENDLQEIAISLVPEIRDVILALESQEGSILSRMSGSGVTCFGIFDSEENAKTAAVNIREKQPEWWVCDAQLIV 2V2V Chain:A ((7-271)) -----VLSPAKINLGLWVLGRLPSGYHEI--LTLYQEIPFYDEIYIREGVLR--------VETNIGIPQEENLVYKGLREFERITGIEINYSIFIQKNIPPGAGLGGGSSNLAVVLKKVNEL--LGSPLSEEELRELVGSISADAPFFLLGKSAIGRGKGEVLEPVET-EISGKITLVIPQVSS-STGRVYSSLREEHFVTPEYAEEKIQRIISGEVEEIENVLGDIARELYPEINEVYRFVEYL--GFKPFVSGSGSTVYFFGGASEELKKAA-----KMRGWKVVELEL--

General information: TITO was launched using: RESULT: Template: 2V2V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131350 for 2214 contacts (-59.3/contact) + 2D Compatibility (PS) -28033 + (NN) -5718 + (LL) 2168 1D Compatibility (HY) -16400 + (ID) 4150 Total energy: -183483.0 ( -82.87 by residue) QMean score : 0.426

(partial model without unconserved sides chains): PDB file : Tito_2V2V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V2V-query.scw PDB file : Tito_Scwrl_2V2V.pdb: